Rated 4.9 excellent | 221 reviews
Rated 4.9 excellent | 221 reviews
Tesamorelin is a synthetic 44-amino-acid analog of growth-hormone–releasing hormone (GHRH), supplied as a high-purity lyophilized powder. It is designed to activate the GHRH receptor on pituitary somatotrophs and is used in in vitro and preclinical research to study endogenous growth hormone release, GH-axis signaling, downstream IGF-1 activity, and metabolic pathway dynamics. Tesamorelin includes an N-terminal trans-3-hexenoyl modification that distinguishes it from native GHRH and improves peptide stability while preserving GHRH receptor activity. Unlike direct growth hormone, tesamorelin acts upstream by stimulating receptor-mediated GH release rather than supplying GH externally.
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